• Opening lecture (45 min)
  • K: keynote (25+5 min)
  • IL: invited lecture (15+5 min)
  • OC: oral contribution (12+3 min)
  • FC: flash communication (5 min)
  • Poster sessions will occur during coffee breaks and lunches

Sunday 25 — Cavallerizza reale

13:00 - 14:30 Registration
14:30 - 14:50 Opening
Chairperson: A. Abbotto
14:50 - 15:35
M. Maggini
Microfluidics: a light touch to nanosystems chemistry
Chairperson: R. Fernández
15:35 - 16:05 B. Martin-Matute
Catalysis in Selective Organic Synthesis: From Discovery to Applications in Late-Stage Functionalizations
16:05 - 16:25 L. Russo
Glycobiomaterials for the generation of artificial patient-personalized tissues: from functionalization strategies to AI guided synthesis
16:25 - 17:00 Coffee break
Chairperson: S. Filippone
17:00 - 17:30 M. Salamone
Factors Governing Reactivity and Selectivity in Hydrogen Atom Transfer Based C(sp3)-H Bond Functionalization
17:30 - 17:50 A. Deagostino
Properly Functionalised ortho-Carboranes as Versatile Platforms for the Synthesis of Anticancer Agents in BNCT (Boron Neutron Capture Therapy) Applications
17:50 - 18:10 R. Pérez
Chemical systems to modulate biological targets
18:30 - 20:00 Welcome cocktail

Monday 26 — Centro di Biotecnologie Molecolari

Chairperson: A. Molinaro
9:00 - 9:30 M. Costas
Minimalistic Models of Oxotransferases as Catalysts for Site and Enantioselective Oxidation of Strong C-H Bonds
9:30 - 9:50 G. Gattuso
A pillar[5]arene-based pseudo[1]catenane as a chiroptical switch
9:50 - 10:10 C. Matassini
Stimuli responsive iminosugars as modulators of β-glucocerebrosidase: smart tools for targeting Parkinson and Gaucher diseases
10:10 - 10:30 I. Alfonso
Supramolecular approaches to chemical biology
10:30 - 11:00 Coffee break
Chairperson: V. Pace
11:00 - 11:30 D. Peña
When organic chemistry meets surface science: from nanographene characterization to single-molecule reactions
11:30 - 11:45 D. Fiorito
Chemoenzymatic catalysis for biomass valorization
11:45 - 12:00 T. Rigotti
Enantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as ortho-disubstituted benzene bioisosteres
12:00 - 12:15 G. Esposito
Unlocking siderophore production in anabaena flos-aquae UTEX 1444: a four-step optimization for their high-yield biosynthesis
12:15 - 12:30 R. López Alvarez
Bifunctional Brønsted base catalysis twards synthetic diversity
12:30 - 12:45 C. Loro
Palladium-catalyzed vicinal diazidation and acetoxy/hydroxylation of N-allyl sulfonamides
12:45 - 12:50 M. Cordaro
Synthesis and applications of amphiphilic Styryl-Pyrene-BODIPYs
12:50 - 12:55 C. Manas
Heterodifunctionalization of Alkynes Promoted Exclusively by Visible Light
12:55 - 13:00 R. Stefania
Symmetrical PSMA-targeted SiPcs with axial Si-O-C and Si-O-Si bonds: photophysical and photochemical properties for cancer PDT treatment
13:00 - 14:30 Lunch + Poster session I
Chairperson: O. Bortolini
14:30 - 15:00 M. Melucci
Chemical tailoring of graphene materials for sensing, carbocatalysis and water remediation
15:00 - 15:20 M. Diéguez
Synergistic appproaches to catalyst design: from benchmark to elusive substrates
15:20 - 15:40 L. Castoldi
Metal-free vinylations with vinylbenziodoxolones
15:40 - 16:00 R. Mancuso
PdI2-catalyzed carbonylative S-heterocyclization processes
16:00 - 16:15 T. Medina Gil
Gold(I)-Catalyzed Intermolecular Aryloxyvinylation with Acetylene Gas
16:15 - 16:30 A. Antoniou
Synthesis of tetraphenylethene L-phenylalanine derivatives and their application in aggregation induced fluorescent peptide materials
16:30 - 17:00 Coffee break + Poster session I
Chairperson: M. Gruttadauria
17:00 - 17:30 L. Dell'Amico
Mechanistic investigations in light-driven synthetic chemistry. From direct photochemistry to organophotoredox catalysis
17:30 - 17:50 V. Costantino
Chemistry: a bridge in multidisciplinary studies to face complex environmental challenges
17:50 - 18:10 F. Juliá
Chemoselective C–N bond assembly under copper catalysis
18:10 - 18:15 A. Velasco Rubio
Ni-catalyzed 1,2-alkylBorylation and silylation of allenes en route to 1,3-Bis-organometallic reagents
18:15 - 18:20 L. Palombi
Nitrogen elusive chirality of enantiopure tosyl-isoindolinone derivatives caught by ECD spectra: an experimental and theoretical investigation
18:20 - 18:25 A. Lecuona Isasa
Synthesis and characterization of carbon quantum dots (CQDs) decorated with enantiomerically pure prolines
18:25 - 18:30 J. Scarfiello
Catalyst-free pyrrolidines synthesis through visible-light aided intramolecular chloroamination-cyclization of N-substituted 4-pentenylamines
18:30 - 18:35 E. Colarusso
Identification of novel hit compounds targeting bromodomain-containing protein 9 (BRD9)

Tuesday 27 — Centro di Biotecnologie Molecolari

Chairperson: B. Gabriele
9:00 - 9:30 N. Martín
Amazing molecular nanographenes
9:30 - 9:50 D. Monge
Anion-Binding Strategies for Asymmetric Catalysis: en route to biologically relevant molecules
9:50 - 10:10 C. Valdés
Geminal difunctionalization of carbonyls via N-sulfonylhydrazones
10:10 - 10:30 M. Alcarazo
Enantioselective synthesis of helicenes
10:30 - 11:00 Coffee break
Chairperson: J. L. Vicario
11:00 - 11:30 A. W. Kleij
Advancing the synthesis of congested stereogenic centers
11:30 - 11:45 P. Rivero Prieto
Targeting Dydroceramide Desaturase 1 (Des1): Syntheses of Ceramide Analogues with a Rigid Scaffold, Inhibitory Assays, and AlphaFold2-Assisted Structural Insights Reveal Cyclopropenone PR280 as a Potent Inhibitor
11:45 - 12:00 F. De Nardi
A green approach to Wittig olefination in Deep Eutectic Solvents
12:00 - 12:15 A. Lledó Ponsati
Cavitand receptors of increased flexibility. Applications in selective molecular recognition
12:15 - 12:30 J. Roletto
API manufacturing through industrial scale up relevant organic chemistry reactions
12:30 - 12:45 I. Bosque
Alkanes in Minisci-type reaction under photocatalytic conditions with hydrogen evolution
12:45 - 12:50 M. Abbate
Straightforward strategy for making mono and bimetallic magnetic nanoparticles using Hyaluronic Acid/Cyclodextrin bioconjugate
12:50 - 12:55 L. Lerena Pérez
New Approaches on Gold(I)-Catalyzed Synthesis of Seven-Ring Linear Acenes
12:55 - 13:00 L. Veltri
Catakytic cyclization of 3-ynamides by CO2 incorporation
13:00 - 14:30 Lunch + Poster session II
Chairperson: A. M. Echavarren
14:30 - 15:00 L. Pignataro
Challenging photocatalytic transformations using donor-acceptor cyanoarene dyes
15:00 - 15:20 O. García Mancheño
A journey towards asymmetric σ-hole catalysis
15:20 - 15:40 A. Mendoza
Redox-active carbenes and surprises in decarboxylative coupling
15:40 - 16:00 I. Pibiri
Fighting Nonsense. Identification of new Translational Readthrough Inducing Drugs (TRIDs)
16:00 - 16:15 V. Muccilli
Synthesis Honokiol and Magnolol dimers as metabolic enzymes inhibitors
16:15 - 16:30 D. Marcos Atanes
Tuning Regioselectivity in Iridium-Catalyzed Aromatic Amide Borylation with CF3-Modified Bipyridine Ligands
16:30 - 17:00 Coffee break + Poster session II
Chairperson: A. Mordini
17:00 - 17:30 S. Menichetti
Thia-bridged triarylamines: a peculiar example of helical shaped molecules
17:30 - 17:50 D. Caprioglio
Regiodivergent Synthesis of ortho- and para-Cannabinoquinones
17:50 - 18:05 G. Giachin
Structural Chemistry of Biomolecules by means of cryo-EM
18:05 - 18:20 A. Fantinati
New synthetic strategies to obtain a precurso of (+/-)-CBD
18:20 - 18:25 L. Ielo
Imines surrogates homologations: non-covalent proteasome inhibitors
18:25 - 18:30 M. Plaza Martínez
Photochemical halogen-bonding assisted generation of alkenyl radicals
18:30 - 18:45 Closing remarks
20:00 - 23:00 Social dinner

Poster session I

PC-01 F. Cadamuro
Collagen glycosylation method exploiting horseradish peroxidase for glycosignature studies at the extracellular matrix level
PC-02 M. Martínez Melero
A new set of complexes based on escorpionate ligands with first row transition metals
PC-03 M. Christodoulou
Inhibiting ferroptosis in pyricularia oryzae
L. Izquierdo Aranda
Silver supported nanoparticles on [Mg4Al-LDH] as an efficient catalyst for the α-alkylation of nitriles, oxindoles and other carboxylic acid derivatives with alcohols
PC-05 S. Serrano Buitrago
Development of a metal-free methodology for easy labelling nucleophiles with BODIPYs
PC-06 M. C. Cancellieri
Chemo-enzymatic stereoselective synthesis of sandalwood fragrances
PC-07 I. Sánchez Sanz
Synthesis of novel gemini-type analogues of maxacalcitol with potential biology activity
PC-08 F. Cardano
Emissive peptide nucleic acids: the case of fluorescent uracil analog
PC-09 A. Granell Fort
Aminofluorination of allyl carbamates with hypervalent iodine reagents: towards the construction of the β-fluoroamino fragment in sphingosine derivatives
PC-10 K. Medrano
Study of tribenzo[b,d,f]azepines as new organic photocatalysts.
PC-11 M. V. Martinez-Diaz
Annulative π-extension of subphthalocyanines
PC-12 S. Dughera
C2-symmetric cycloglicerodiphosphates as efficient catalysts for enantioselective reactions
PC-13 Q. Zeng
Stereoselective three-component allylic alkylation enabled by dual photoredox/Ni catalysis
PC-14 C. Meazzo
One-pot, telescoped alkenylation of amides via stable tetrahedral intermediates as lithium enolate precursors
PC-15 A. Delgado
Functional CO2-based polycarbonates en route to circular materials
PC-16 J. Humbrías Martín
Photocatalytic ring expansion of alkenyl sulfonium salts
PC-17 F. Scarchilli
Highly selective C(sp3)–H bond oxygenation at remote methylenic sites enabled by polarity enhancement
PC-18 S. Cananà
Asymmetric reduction of cyclic imines by imine reductase enzymes in non-conventional solvents
PC-19 D. J. Cárdenas
Ni-catalyzed cycloisomerization and cyclodimerization of allenynes
PC-20 A. Bossoni
Design, synthesis and further perspective of probe 10, a selective ALDH-1A3 curcumin-based fluorescent probe
PC-21 C. Saá
One-pot Rh(III)-catalyzed double annulation of N-arylpyrroles with alkynes: a sustainable route to photo- and electro-active ullazines
PC-232td> C. Momoli
Synthesis of polycyclic quinoline fused steroids by Friedländer-type reaction
PC-23 G. Blay
Enantioselective conjugate addition of isocyanoacetate esters to aurone-derived imines
PC-24 V. Di Matteo
Stereostructural determination of a new cyanochelin from the cyanobacterium leptolyngbya
PC-25 L. M. Ferreira
Synthesis of hybrid compounds based on quinoline and naphthohydroquinone and its antioxidant activity
PC-26 D. Illuminati
(L)-mono-methyl tyrosine (Mmt): new synthetic strategy via bulky ‘forced-traceless’ regioselective Pd-catalyzed C(sp2)–H activation

Poster session II

PC-27 D. Tarr
Addressing the challenges of asymmetric hydrogenation of exocyclic benzofused-based alkenes with new Ir-P,N catalysts
PC-28 M. C. Cabua
Mac methodology for the rapid and stereoselective synthesis of anti 2-hydroxy-1,3-diamine scaffolds present in anti-HIV agents
PC-29 G. Agnoloni
Design, synthesis, and study of chiral systems with spin selectivity in electron transfer processes for the control of molecular spin qubits
PC-30 A. Odoardo
Organocatalytic synthesis and properties study of poly(hydroxymethylfuroate), bio-based polyester derived by 5-hydroxymethylfurfural
PC-31 D. Franchi
Sustainable cross-coupling protocol: Miyaura borylation and one-pot Suzuki-Miyaura reaction in deep eutectic solvents (DES)
PC-32 S. Timmann
Synthetic applications of sulfonium salts
PC-33 J. Garrido
Evaluation of organophotocatalysts stability: a high-throughput approach
PC-34 M. Cárcel
Boosting cyclotrimerization reactions through cobalt catalysts
PC-35 P. Quagliotto
Claisen micellar synthesis of chalcones. The surfactant role and selectivity
PC-36 E. Reyes
Asymmetric desymmetrization of cyclobutane derivatives
PC-37 F. Marra
Organolithium-induced kinetic resolution and anionic fries rearrangement of o-aryl carbamates
PC-38 M. Martínez Estévez
Exploring the cytotoxicity of cyclometallated Ru(II) for cancer treatment
PC-39 V. Ponnarassery Aravindakshan
Benzothiazoline derivatives for fluorescence image-guided surgery; a new methodology to avoid oxidation to benzothiazole
PC-40 N. Méndez Gil
High surface area polymers based on truxene and triindol monomers for efficient iodine waste remediation
PC-41 M. Fresia
DNA detection with amphiphilic ndi probes
PC-42 P. Galloni
Carboxylic acids pKa determination through DFT methods
PC-43 F. Mancusi
Synthesis of smart nanomaterials with potential antibiofilm activity for coating medical devices
PC-44 O. Pàmies
Chiral tetrahydrofuran-fused spyrocylic scaffolds via [3+2] cycloaddition reaction. From batch to flow
PC-45 R. Gnavi
Oxidative anionic homo-fries rearrangement under bench-type aerobic conditions
PC-46 S. Filippone
Enantioselective synthesis of molecular nanographenes
PC-47 S. Toldo
Immobilization of chiral mono-amidine catalysts for stereoselective aza-henry reaction under heterogeneous phase
PC-48 D. Ghorai
Regio- and enantio-selective Ni-catalyzed synthesis of branched 1,5-dienes featuring a quaternary stereogenic center
PC-49 B. L. Tóth
Alkynyl cyclic carbonates as masked 1,3-enyne reagents in photo-reductive cobalt-catalyzed couplings
PC-50 A. Rey López
Ligand enabled regio- and site-selective intermolecular hydrocarbonation of allenes: straight access to scaffold bearing tertiary and quaternary carbon centers
PC-51 A. Palone
C-H bonds as functional groups: simultaneous generation of multiple stereocenters by enantioselective hydroxylation at unactivated tertiary C-H bonds
PC-52 D. Valcarreras
Redox-active carbenes as a functionalization platform for alkane feedstocks